Psychiatr. pro Praxi, 2002; 1: 15-19

Epilepsie - psychóza, stále nejasný vztah?

prof. MUDr. Josef Faber DrSc
Neurologická klinika, Fakultní nemocnice Praha-Bulovka

Keywords: psychosis, epilepsy, neurotransmitter systems, learning models, limbic system.

Published: December 31, 2002  Show citation

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Faber J. Epilepsie - psychóza, stále nejasný vztah? Psychiatr. praxi. 2002;3(1):15-19.

Literatura je k tématu uvedeném v záhlaví stále nejednotná, ale přibývá faktů udávajících unionistické tendence. Společným jmenovatelem pro epileptické a psychotické choroby jsou poznatky o receptorech a humoroergních systémech. Jedna hypotéza však nevysvětlí všechny psychózy a všechny epilepsie. Avšak některé krátké stereotypně se chovající psychotické ataky a některé komlexní i simlexní fokální temporální epilepsie budou mít k sobě blízko, jejich společným jmenovatelem bude epileptický fokus v limbickém systému a nevyváženost mezi různými humoroergními systémy kmenovými a subkortikálními. Stereo-EEG se zanořenými elektrodami a moderní vyšetřovací metody jako je PET (pozitronová emisní tomografie) nebo funkční NMR (nukleární magnetická rezonance) a vysoce rozlišovací EEG s novými matematickými analytickými metodami nám pomohou tyto problémy řešit.

Epilepsy - Psychosis, an as yet unclear relationship?

The literature on this subject still lacks unanimity, but the facts supporting a unanimous theory have been increasing. What epilepsy and psychotic disorders have in common is a knowledge of the receptors and systems of neurotransmitters. One hypothesis, however, cannot explain all psychotic diseases and all types of epilepsy. But some brief stereotypically recurrent psychotic attacks and some types of complex and simple focal temporal epilepsy seem to be related, the common denominator perhaps being an epileptic focus in the limbic system and a disbalance among various stem and subcortical systems of neurotransmitters. Stereo-EEG with dipped electrodes and up to date diagnostic methods like PET (positron emission tomography), functional MRI and high resolution EEG, combined with new mathematical analytical methods, could help us to resolve these problems.

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