Psychiatr. pro Praxi, 2002; 4: 158-160

Zmiešané afektívne stavy: dysforická mánia

prof. MUDr. Eva Hadašová CSc
Farmakologický ústav lékařské fakulty Masarykovy univerzity, Brno

Keywords: polypharmacotherapy, psychotropic drugs, drug interactions, pharmacokinetics, pharmacodynamics.

Published: December 31, 2002  Show citation

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Hadašová E. Zmiešané afektívne stavy: dysforická mánia. Psychiatr. praxi. 2002;3(4):158-160.

Článek podává základní informaci o farmakologickém riziku polyfarmakoterapie v psychiatrii. Jsou diskutovány výhody a nevýhody, které může přinášet kombinační léčba v psychiatrii a popsány možné mechanizmy interakcí na farmakokinetické a farmakodynamické úrovni.

PITFALLS OF POLYPHARMACOTHERAPY

The present paper supplies basic information about the pharmacological risks of polypharmacotherapy in psychiatry. The positive features and the drawbacks of combined therapy are discussed and the possible mechanisms of drug interactions on the pharmacokinetic and pharmacodynamic levels are described.

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References

  1. Akiskal HS, Mallya G. Criteraia for the, ,soft" bipolar spectrum: treatment implications. Psychopharmacol. Bull 1987; 23: 68-73. Go to PubMed...
  2. Akiskal HS, Bourgeois ML, Angst J, Post R, et al. Re-evaluating the prevalence of and diagnostic composition within the broad clinical spectrum of bipolar disorders. J. Affective Disorders 2000; 59: 5-30. Go to original source... Go to PubMed...
  3. Bauer MS, Wybrow PC, Winokur A. Rapid cycling bipolar affective disorder, association with grade I hypothyroidism. Arch Gen Psychiatry 1990; 47: 427-432. Go to original source... Go to PubMed...
  4. Bunney WE, Goodwin FK, Murphy DL. The, ,switch pro-cesses" in manic-depressive illness, III: theoretical iplications. Arch Gen Psychiatry 1972; 27: 312-317. Go to original source... Go to PubMed...
  5. Calabrese JR, Delucchi GA. Spectrum of efficacy of valproat in 55 patients with rapid-cycling bipolar disorder. Am J Psychiatry 1990; 147: 431-434. Go to original source... Go to PubMed...
  6. Carlson GA, Goodwin FK. The stages of mania: a longitudinal analysis of the manic episode. Arch Gen Psychiatry 1973; 28: 221-228. Go to original source... Go to PubMed...
  7. Cohen S, Khan A, Robins J. Significance of Mixed Features in Acute Mania. Comprehensive Psychiatry 1988; 29, 4: 4212-4226. Go to original source... Go to PubMed...
  8. Court J. The continuum model as a resolution of paradoxes in manic depressive psychoses. Br J Psychiatry 1972; 120: 133-141. Go to original source... Go to PubMed...
  9. Dilsaver SC, Chen YR, Swann AC, et al. Suicidality, panic disorder and psychosis in depressive-mania an pure mania. Psychiatry Res 1997; 73: 47-56. Go to original source... Go to PubMed...
  10. Dilsaver SC, Chen YR, Shoaib AM, Swann AC. Phenomenology of mania: Evidence for distinct depressed, dysforic and euforic presentations. Am J Psychiatry 1999; 156: 426-430. Go to original source... Go to PubMed...
  11. Evans DL, Nemeroff CHB. The Dexamethasone Suppressione Test in Mixed Bipolar Disorder. Am J Psychiatry 1983; 140: 615-617. Go to original source... Go to PubMed...
  12. Godlberg JL, Garno JL, Leon AC, et al. Association of reccurent suicidal ideation with nonremission from acute mixed mania. Am J Psychiatry 1998; 155: 1753-1755. Go to original source... Go to PubMed...
  13. Himmelhoch JM, Garfinkel ME. Mixed mania: Diagnosis and treatment. Psychopahramcol Bull 1986; 22: 613-620.
  14. Keller MB, Lavori PW, Coryel W, et al. Differential Outcome of Pure Manic, Mixed/Cycling, and Pure Depressive Episodes in Patinets with Bipolar Illness. JAMA 1986; 255, 3: 3138-3142. Go to original source...
  15. McElroy SL, Keck PE, Pope HG, et al. Clinical and Research Implications of the Diagnosis of Dysforic or Mixed Mania or Hypomania. Am J Psychiatry 1992; 149: 1633-1644. Go to original source... Go to PubMed...
  16. Mc Elroy SI, Strakowski SM, Keck PE, et al. Differences and similarities i nmixed and pure mania. Compreh Psychiatry 1995; 36: 184-194. Go to original source... Go to PubMed...
  17. Mezinárodní klasifikace nemocí, 10. revize. Duševní poruchy a poruchy chování. Praha, Psychiatrické centrum 1992: 282 s.
  18. Montgomery SA, Keck PE. First international exchange on Bipolar Disorder J Affect Disorders 2000; 59: 81-88. Go to original source... Go to PubMed...
  19. Montgomery SA, Schatzberg AF, Guelfi JD, Kasper S, et al. Pharmacotherapy of depression and mixed states in bipolar disorder. J Affect Disorders 2000; 50: 39-56. Go to original source... Go to PubMed...
  20. Nunn CM. Mixed Affective States and Natural History of Manic-Depressive Psychosis. Brit J Psychiatry 1979; 134: 153-160. Go to original source... Go to PubMed...
  21. Perugi G, Akiskal HS, Micheli C, et al. Clinical subtypes of bipolar mixed states. Validating a broder European definition in 143 case. J Affect Disordr 1997; 43: 169-180. Go to original source... Go to PubMed...
  22. Post RM, Rubinow DR, Uhde TW, et al. Dysforic mania: clinical and biological correlates. Arch Gen Psychiatry 1989; 46: 353-358. Go to original source... Go to PubMed...
  23. Post RM, Uhde TW, Roy Byrne PP, Joffe RT. Correlates of antimanic responses to to carbamazepin. Psychiatry Res 1987; 21: 71-83. Go to original source... Go to PubMed...
  24. Secunda SK, Swann A, Katz MM, et al. Diagnosis and Treatment of Mixed Mania. Am J Psychiatry 1987; 144: 96-98. Go to original source... Go to PubMed...
  25. Swann AC, Stokes PE, Casper R, Secunda SK, et al. Hypotalamic-pituitary-adrenocortical function in mixed and pure mania. Acta apsychiatr Scand 1992; 85: 270-274. Go to original source... Go to PubMed...
  26. Swan AS, Bowden CL, Morris D, Calabrese JR, et al. Depression during mania. Treatment response to lithium or divalproex. Arch Gen Psychiatry 1997; 54: 37-42. Go to original source... Go to PubMed...
  27. Tandon R, Channabasavanna SM, Greden JF. CSF biochemical correlates of mixed affective states. Acta Psychiatr Scand 1988; 78: 289-297. Go to original source... Go to PubMed...




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