Psychiatr. pro Praxi, 2008; 9(1): 8-11

Depression in elderly

MUDr. Radim Kubínek, doc. MUDr. Vladimír Pidrman Ph.D
Psychiatrická klinika FN a LF UP, Olomouc

The article discusses depression in elderly as serious interdisciplinar disorder. Basic etiological factors and symptomatological differencies of the depression in elderly are mentioned as well. The possibility of improved diagnostic is reflected in the intence of interdisciplinary cooperation. The article discusses optimal treatment. The specific pharmacoterapeutics aspects, new knowledge of the possibilities and limits of antidepressants are described.

Keywords: antidepressants, biological factors, depression, psychosocial factors, elderly

Published: February 1, 2008  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Kubínek R, Pidrman V. Depression in elderly. Psychiatr. praxi. 2008;9(1):8-11.
Download citation

References

  1. Alexopoulos GS, Katz IR, Reynolds CF, Carpenter D, Docherty JP. Pharmacotherapy of depressive disorders in older patients. Comprehensive NeuroScience Inc., New York, 2001, 76 s.
  2. Alves TC, Rays J, Telles RM et al. Effects of antidepressant treatment on cognitive performance in elderly subjects with heart failure and comorbid major depression: an exploratory study. Psychosomatics, 2007; 48(1): 22-30. Go to original source... Go to PubMed...
  3. Barak Y, Olmer A, Aizenberg D. Antidepressants redukce the risk of suicide aminy elderly depressed patients. Neuropsychopharmacology, 2006; 31(1):178-181. Go to original source... Go to PubMed...
  4. Beekman ATF, Deeg DJH, van Tilburg T et al. Major and minor depression in later life: a study of prevalence and risk factors. J Affective Disorders 1995; 36: 65-75. Go to original source... Go to PubMed...
  5. Blazer D, Hughes DC, Georg LK. The epidemiology of depression in an elderly community population. Gerontologist 1987; 27: 281-287. Go to original source... Go to PubMed...
  6. Brenes GA, Williamson JD, Messier SP et al. Treatment of minor depression in older adults: a pilot study comparing sertraline and exercise. Aging Ment Health, 2007; 11(1): 61-68. Go to original source... Go to PubMed...
  7. Dew MA, Whyte EM, Lenze EJ, Houck PR et al. Recovery from major depression in older adults receiving augmentation of antidepressant pharmacotherapy. Am J Psychiatry, 2007; 164(6): 892-899. Go to original source... Go to PubMed...
  8. Filocamo MT, Li Marzi V, Del Popolo G, Cecconi F, Villari D, Marzocco M, Nicita G. Pharmacologic treatment in postprostatectomy stress urinary incontinence. Eur Urol, 2007; 51(6): 1559-1564. Go to original source... Go to PubMed...
  9. Grossberg GT, Stehelin HB, Mesina JC, Anand R, Veach J. Lack of adverse pharmacodynamic drug interactions with rivastigmine and twenty-two classes of medications. Int J Geriatr Psychiatry 2002; 15: 242-247. Go to original source...
  10. Healthy Ageing. A Chalange for Europe; The Swedish National Institute of Public Health. Stockholm 2006.
  11. Health Promotion Glossary; WHO, Geneva 1998.
  12. Holmerová I, Vaňková H, Jurašková B. Deprese ve stáří. In: Deprese z různých úhlů pohledu II. Praha, Galén, 2007; 93-123.
  13. Holmerová I, Vaňková H, Dragomirecká E, Janečková H, Veleta P. Depresivní syndrom u seniorů, významný a dosud nedoceněný problém. Psychiat. pro Praxi, 2006; 4: 182-184.
  14. Hunkeler EM, Katon W, Tang L, Williams JW Jr et al. Long term outcomes from the IMPACT randomised trial for depressed elderly patients in primary care. BMJ, 2006; 332(7536): 259-263. Go to original source... Go to PubMed...
  15. Chen Z, Skolnick P. Triple uptáme inhibitors: therapeutic potential in depression and beyond. Expert Opin Investic Drugs, 2007; 16(9): 1365-1377. Go to original source... Go to PubMed...
  16. Jacobson SA, Preis RW, Greenblatt DJ. Handbook of geriatric psychopharmacology. American Psychiatric Publishing Inc., Washington DC, 2002; 445 s.
  17. Jirák R. Deprese u seniorů - biologické a psychosociální vlivy, vztahy deprese a demence. Psychiatr. pro Praxi, 2007; 8(5): 198-200.
  18. Khan A, Schwarz K A, Kolts RL, Brown WA. BMI, sex, and antidepressants response. J Affect Disord, 2007; 99(1-3): 101-106. Go to original source... Go to PubMed...
  19. Levy RH, Collins C. Risk and predictability of drug interactions in the elderly. Int Rev Neurobiol, 2007; 81: 235-251. Go to original source... Go to PubMed...
  20. Lepine JP, Bouchez S. Epidemiology of depression in the elderly. Int Clin Psychopharmacol 1998. Go to original source...
  21. Mottram P, Wilson K, Strobl J. Antidepressants for depressed elderly. Cochrane Database Syst Rev. 2006; (1): CD003491. Go to original source...
  22. Pidrman V. Deprese a kardiovaskulární onemocnění. 3. rozšířené vydání, Maxdorf, Praha, 2004; 68 s.
  23. Pidrman V. Deprese seniorů. Praha, Maxdorf, 2003; s. 60.
  24. Reynolds CF, Dew MA, Pollock BG, Mulsant BH, Frank E. Maitenance treatment of major depression in old age. N Engl J Med, 2006; 16; 354(11): 1130-1138. Go to original source... Go to PubMed...
  25. Richards JB, Papaioannou A, Adachi JD, Joseph L, Whitson HE et al. Effect of selective serotonin reuptake inhibitors on the risk of fracture. Arch Intern Med, 2007; 22; 167(2):188-194. Go to original source... Go to PubMed...
  26. Reuben BD, Herr KA, Pacala JT et al. Geriatrics. Blackwell Publishing Inc., Malden, 2003; 240 p.
  27. Savaskan E, Müller SE, Böhringer A, Schulz A, Schächinger H. Antidepressive therapy with escitalopram improves mood, cognitive symptoms, and identity memory for angry faces in elderly depressed patients. Int J Neuropsychopharmacol, 2007; 1-8. Go to original source...
  28. Schaltberg AF, Cole JO, DeBatista C. Manual of clinical psychopharmacology. American Psychiatric Publishing Inc. Washington DC, 2003; 700 p.
  29. Sneed JR, Roose SP, Keilp JG, Krishnan KR, Alexopoulos GS, Sackeim HA. Response inhibition predicts poor antidepressant treatment response in very old depressed patients. Am J Geriatr Psychiatry, 2007; 15(7): 553-563. Go to original source... Go to PubMed...
  30. Thompson S, Herrmann N, Rapoport MJ, Lanctôt KL. Efficacy and safety of antidepressants for treatment of depression in Alzheimer´s disease: a metaanalysis. Can J Psychiatry, 2007; 52(4): 248-255. Go to original source... Go to PubMed...
  31. Unützer J, Tang L, Oishi S et al. Reducing suicidal ideation in depressed older primary care patients. J A Geriatr Soc, 2006; 54(10): 1550-1556. Go to original source... Go to PubMed...




Psychiatry for Practice

Madam, Sir,
please be aware that the website on which you intend to enter, not the general public because it contains technical information about medicines, including advertisements relating to medicinal products. This information and communication professionals are solely under §2 of the Act n.40/1995 Coll. Is active persons authorized to prescribe or supply (hereinafter expert).
Take note that if you are not an expert, you run the risk of danger to their health or the health of other persons, if you the obtained information improperly understood or interpreted, and especially advertising which may be part of this site, or whether you used it for self-diagnosis or medical treatment, whether in relation to each other in person or in relation to others.

I declare:

  1. that I have met the above instruction
  2. I'm an expert within the meaning of the Act n.40/1995 Coll. the regulation of advertising, as amended, and I am aware of the risks that would be a person other than the expert input to these sites exhibited


No

Yes

If your statement is not true, please be aware
that brings the risk of danger to their health or the health of others.