Psychiatr. pro Praxi, 2008; 9(6): 269-272

SCHIZOPHRENIA AND SUBSTANCE USE DISORDERS

MUDr. Michal Maršálek CSc
Psychiatrická léčebna Bohnice, Praha

Epidemiological studies found that patients with schizophrenia are 3 times more likely to have substance use disorders than persons without mental illness. Substance abuse in schizophrenia increased positive symptoms, agressivity, suicidality, number of relapses and rehospitalisations, and poorer treatment compliance. In particular, cannabis, amphetamine, cocaine and alcohol has been reported to be with psychotogenic effect in schizophrenia. To date, the efficacy of the first generation antipsychotics in the treatment of substance abuse have been mixed. On the contrary, certain second generation antipsychotics seem to be particularly promising.

Keywords: Key words: schizophrenia, substance abuse disorders, epidemiology, antipsychotics.

Published: December 1, 2008  Show citation

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Maršálek M. SCHIZOPHRENIA AND SUBSTANCE USE DISORDERS. Psychiatr. praxi. 2008;9(6):269-272.
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