Psychiatr. praxi. 2012;13(3):108-110

New advancements in biological psychiatry

prof.MUDr.Eva Češková, CSc.¹, prof.MUDr.Ladislav Hosák, Ph.D.^2,3, doc.MUDr.Roman Jirák, CSc.⁴, doc.MUDr.Tomáš Kašpárek, Ph.D.¹, MUDr.Michal Maršálek, CSc.⁵, doc.MUDr.Radovan Přikryl, Ph.D.¹

¹ Středoevropský technologický institut, MU (CEITEC-MU), Psychiatrická klinika LF MU a FN Brno

² Katedra interních oborů, Ostravská univerzita v Ostravě, LF a Oddělení psychiatrické, FN Ostrava

³ Psychiatrická klinika, UK v Praze, LF v Hradci Králové a FN Hradec Králové

⁴ Psychiatrická klinika, UK v Praze, 1. LF a VFN v Praze

In the genetics of mental disorders, the main effort of the scientists is recently aimed at genome-wide association studies and the detection

of DNA microdeletions/microduplications. They seem to be important as one of the substantial parts of the genetic background

of schizophrenia. Brain neuroimaging seeks to define biomarkers, useful in the diagnostics and treatment of mental disorders. Based

on the new knowledge, modern treatments in dementia in Alzheimer´s disease are developed, e.g. anti-amyloid therapy or modulators

of mitochondrial metabolism. Catatonia is still looking for its proper place in the new concepts of classification of mental disorders.

Individual subtypes of catatonia are probably different from each other in etiopathogenesis and treatment. In the area of pharmacotherapy,

several guidelines were recently published by the World Federation of Societies of Biological Psychiatry. New brain stimulation

techniques may be efficient in the treatment of depression and schizophrenia.

Keywords: genetics, brain imaging, dementia, catatonia, pharmacotherapy, brain stimulation techniques

Published: November 1, 2012  Show citation