Psychiatr. praxi. 2015;16(1):6-10
Agomelatine is a syntetic analogue of melatonin, agonist of melatonergic MT1, MT2 and antagonist of serotonergic 5-HT2C recceptors.
Agomelatine is antidepressant with unique pharmacological profile which it differs agomelatine from other antidepressant drugs like
SSRI and SNRI in efficacy, tolerability. The article focuses on its efficacy in depression treatment, its diference from SSRI and SNRI, and
its use in clinical practice, in patiens with somatic disorders.
Published: April 20, 2015 Show citation