Psychiatr. praxi. 2015;16(1):24-26

Pregabalin therapy in generalized anxiety disorder and alprazolam dependence

MUDr.Juraj Tkáč
Poliklinika Dům zdraví, Ambulance ADIKTA s. r. o., Jihlava

Prescription drug misuse and abuse are also common problems in primary care settings. Substances of abuse have profound effects on

neurotransmitter systems involved in the pathophysiology of anxiety disorders and, with chronic use, may unmask a vulnerability or

lead to organic changes that manifest as an anxiety disorder.

Generalized anxiety disorder (GAD) follows a chronic period with low rates of remission and frequent relapses. Comorbid substance use

disorder decreases the likelihood of recovery from GAD and increases the risk of exacerbation.

Keywords: pregabalin, anxiety, generalized anxiety disorder, drug dependence

Published: April 20, 2015  Show citation

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Tkáč J. Pregabalin therapy in generalized anxiety disorder and alprazolam dependence. Psychiatr. praxi. 2015;16(1):24-26.
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