Psychiatr. praxi 2019; 20(3): 120-124 [Neurol. praxi. 2019;20(3):214-218]

Treatment of depressive disorders in pain syndromes

MUDr. Martin Hýža
Psychiatrické oddělení, Fakultní nemocnice Ostrava
Katedra neurologie a psychiatrie, Lékařská fakulta, Ostravská univerzita, Ostrava

Comorbidity of depressive disorder and chronic pain is very common in clinical practice. It is connected to worse prognosis and
more severe symptoms of both of them. A recognition of depressive disorder is the most important as it is often manifested with
somatic symptoms only. Common neurobiological mechanisms clarify the effectivity of antidepressants and psychotherapy in
treatment of pain. Both noradrenergic and serotonergic effect is needed for analgesic effect, so the older tricyclic antidepressants
and newer dual antidepressants SNRI are used.

Keywords: depressive disorder, pain, antidepressants, psychotherapy

Published: October 11, 2019  Show citation

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Hýža M. Treatment of depressive disorders in pain syndromes. Psychiatr. praxi. 2019;20(3):120-124.
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