Psychiatr. praxi. 2024;25(2):62-70 | DOI: 10.36290/psy.2024.011

Toxic psychosis and its clinical significance

Mgr. Ing. Irena Semančíková^{1, 2}, MUDr. Miloslav Kopeček, Ph.D.^{3, 4}, prof. Mgr. Ondřej Bezdíček, Ph.D.¹

¹ Neurologická klinika a Centrum klinických neurověd, 1. lékařská fakulta Univerzity Karlovy a Všeobecná fakultní nemocnice v Praze

² Psychiatrická nemocnice Bohnice, Praha

³ Národní ústav duševního zdraví, Klecany

⁴ Klinika psychiatrie a lékařské psychologie, 3. lékařská fakulta Univerzity Karlovy, Praha

The review article focuses on the diagnostics, clinical symptoms and therapy of "toxic psychoses", i.e., substance-induced psychotic disorders, the prevalence of which increased significantly in recent decades due to a considerable increase in the production and consumption of psychoactive substances. This is a type of mental and behavioral disorders caused by the use of psychoactive substances, resulting in secondary psychosis. Differential diagnostics focuses mainly on distinguishing the symptoms of toxic psychosis from schizophrenia, where especially positive symptomatology can overlap. Due to the heterogeneity of the group of toxic psychoses, the article further focuses on distinguishing individual forms according to the inducing psychoactive substance, including their therapy.

Keywords: psychosis, substance, diagnostics, methamphetamine, cannabis.

Accepted: May 29, 2024; Published: June 3, 2024  Show citation