Psychiatr. pro Praxi, 2006; 6

TREATMENT OF DEMENTIA OF THE ALZHEIMER TYPE BY MEMANTINE

MUDr. Elena Žigová
Gerontopsychiatrické oddelenie Psychiatrickej nemocnice PP v Pezinku

The article treats the subject of basic pathogenetic factors of the development of dementia of the Alzheimer type (DAT), of current knowledge and possibilities of pharmacological influence of the dynamics and effects of the neurodegenerative changes in the brain and of cellular death. The focus is on the role of glutamatergal transmission in the pathogenesis of DAT and the possibilities of therapeutic influence of memanthin. The results of clinical studies of effectiveness of treatment by memanthin and the results of post marketing clinical study ELPACH in Slovakia are cited. The practical recommendations for the treatment by memanthin are summarized in the conclusion of the article.

Keywords: dementia, neurodegeneration, excitotoxicity, cellular death, glutamat, antialzheimerics, memantine

Published: February 1, 2007  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Žigová E. TREATMENT OF DEMENTIA OF THE ALZHEIMER TYPE BY MEMANTINE. Psychiatr. praxi. 2006;7(6):.
Share...
Download citation
  • BibTeX (.bib)
  • Bookends (.ris)
  • EasyBib (.ris)
  • EndNote (.enw)
  • EndNote 8 (.xml)
  • ISI WoS (.isi)
  • Medlars (.medlars)
  • Mendeley (.ris)
  • MODS (.xml)
  • Papers (.ris)
  • RefWorks (.txt)
  • RefManager (.ris)
  • RIS (.ris)
  • MS Word (.xml)
  • Zotero (.ris)

    • Return to the content


    Psychiatry for Practice

    Madam, Sir,
    please be aware that the website on which you intend to enter, not the general public because it contains technical information about medicines, including advertisements relating to medicinal products. This information and communication professionals are solely under §2 of the Act n.40/1995 Coll. Is active persons authorized to prescribe or supply (hereinafter expert).
    Take note that if you are not an expert, you run the risk of danger to their health or the health of other persons, if you the obtained information improperly understood or interpreted, and especially advertising which may be part of this site, or whether you used it for self-diagnosis or medical treatment, whether in relation to each other in person or in relation to others.

    I declare:

    1. that I have met the above instruction
    2. I'm an expert within the meaning of the Act n.40/1995 Coll. the regulation of advertising, as amended, and I am aware of the risks that would be a person other than the expert input to these sites exhibited

    No
    Yes

    If your statement is not true, please be aware
    that brings the risk of danger to their health or the health of others.