Psychiatr. praxi. 2015;16(2):64-66

Neurosyphilis

MUDr.Michal Vodička
Psychiatrické oddělení Nemocnice České Budějovice, a.s.

Neurosyphilis is a severe form of syphilitic infection, which can occur during any stage of the disease. It may not manifest itself at all,

but it can also cause severe brain damage in the form of meningitis, multiple psychiatric symptoms or late neurological manifestations.

Keywords: neurosyphilis, tabes dorsalis, gumma, TPHA

Published: May 18, 2015  Show citation

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Vodička M. Neurosyphilis. Psychiatr. praxi. 2015;16(2):64-66.
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References

  1. Lukehart SA, Hook EW, 3rd, Baker-Zander SA, Collier AC, Critchlow CW, Handsfield HH. Invasion of the central nervous system by Treponema pallidum: Implications for diagnosis and treatment. Ann Intern Med 1988; 109: 855-862. Go to original source... Go to PubMed...
  2. Raiziss GW, Severac M. Rapidity with which Spirochaeta pallida invade the bloodstream. Arch Derm Syphilol 1937; 35: 1101-1109. Go to original source...
  3. Collart P, Franceschini P, Durel P. Experimental rabbit syphilis. Br J Vener Dis 1971; 47: 389-400. Go to original source... Go to PubMed...
  4. Keidel A, Moore JE. Studies in asymptomatic neurosyphilis I: A tentative classification of early asymptomatic neurosyphilis. Arch Neurol Psychiatry 1921; 6: 286-291. Go to original source...
  5. Moore JE. Asymptomatic neurosyphilis V: A comparison of early and late asymptomatic neurosyphilis. Arch Derm Syphilol 1928; 18: 99-108. Go to original source...
  6. Merritt HH. The early clinical and laboratory manifestations of syphilis of the central nervous system. N Engl J Med 1940; 223: 446-450. Go to original source...
  7. Moore JE. The relation of neurorecurrences to late syphilis: A clinical study of eighty-one cases. Arch Neurol Psychiatry 1929; 21: 117-136. Go to original source...
  8. Moore JE. The modern treatment of syphilis, 2nd ed. Baltimore: Charles C. Thomas, 1943.
  9. Clark EG, Danbolt N. The Oslo study of the natural history of untreated syphilis; an epidemiologic investigation based on a restudy of the Boeck-Bruusgaard material: A review and appraisal. J Chronic Dis 1955; 2: 311-344. Go to original source... Go to PubMed...
  10. Rockwell DH, Yobs AR, Moore MB Jr. The Tuskegee study of untreated syphilis: The 30th year of observation. Arch Intern Med 1964; 114: 792-798. Go to original source... Go to PubMed...
  11. Merritt HH, Adams RD, Solomon HC. Neurosyphilis. New York: Oxford University Press, 1946.
  12. Adams RD, Merritt HH. Meningeal and vascular syphilis of the spinal cord. Medicine 1944; 23: 181-214. Go to original source...
  13. Stokes JH. Modern clinical syphilology. Philadelphia, PA: W.B. Saunders Company, 1926.
  14. Merritt HH, Moore M. The Argyll Robertson pupil: An anatomic-physiologic explanation of the phenomenon, with a survey of its occurrence in neurosyphilis. Arch Neurol Psychiatry 1933; 30: 357-373. Go to original source...
  15. Dewhurst K. The neurosyphilitic psychoses today: A survey of 91 cases. Br J Psychiatry 1969; 115: 31-38. Go to original source... Go to PubMed...
  16. Romberg EH. Pupillary disturbances in tabes. Zeitschrift Fur Die Gesamte Neurologie Und Psychiatrie 1939; 165: 369-372. Go to original source...
  17. Weinert LS, Scheffel RS, Zoratto G, Samios V, Jeffmann MW, Dora JM, Goldani LZ. Cerebral syphilitic gumma in HIV-infected patients: Case report and review. Int J STD AIDS 2008; 19: 62-64. Go to original source... Go to PubMed...
  18. Kofman O. The changing pattern of neurosyphilis. Can Med Assoc J 1956; 74: 807-812. Go to PubMed...
  19. Hotson JR: Modern neurosyphilis: A partially treated chronic meningitis (Medical Progress). West J Med 1981; 135: 191-200.
  20. Centers for Disease Control and Prevention; Workowski KA, Berman SM. Sexually transmitted diseases treatment guidelines. MMWR Recomm Rep 2006; 55: 1-94.




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