Psychiatr. praxi 2017; 18(2): 78-80 | DOI: 10.36290/psy.2017.015

Pregabalin in the treatment of generalized anxiety disorder

MUDr. Martin Hýľa
Psychiatrické oddělení, Fakultní nemocnice Ostrava
Katedra neurologie a psychiatrie, Lékařská fakulta, Ostravská univerzita

Generalized anxiety disorder is one of the most common anxiety disorders. Pregabalin is unique due to its mechanism of action

among other anxiolytics. It´s effectiveness is proven both in acute and long-term phase of treatment. The case report narrates its

use in a patient resistant to prescribed antidepressants and further good therapeutic response to pregabalin.

Keywords: anxiety, anxiolytics, pregabalin, treatment

Published: July 1, 2017  Show citation

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Hýľa M. Pregabalin in the treatment of generalized anxiety disorder. Psychiatr. praxi. 2017;18(2):78-80. doi: 10.36290/psy.2017.015.
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References

  1. Mackintosh MA, Gatz M, Wetherell JL, Pedersen NL. A twin study of lifetime generalized anxiety disorder (GAD) in older adults: genetic and environmental influences shared by neuroticism and GAD. Twin Res Hum Genet 2006; 9: 30-37. Go to original source...
  2. American Psychiatric Association. Diagnostic and statistical manual of mental disorders (5th ed.) Washington, DC: American Psychiatric Association; 2013. Go to original source...
  3. Allgulander Ch. Generalized anxiety disorder: A review of recent findings. J Exp Clin Med 2012; 4(2): 88-91. Go to original source...
  4. Perna G, Alciati A, Riva A, Micieli W, Caldirola D. Long-term pharmacological treatments of anxiety disorders: an updated systematic review. Curr Psychiatry Rep 2016; 18: 23. Go to original source... Go to PubMed...
  5. Pollack MH. Refractory generalized anxiety disorder. J Clin Psychiatry 2009; 70(suppl 2): 32-38. Go to original source...
  6. Wetherell JL, Petkus AJ, White KS, Nguyen H, Kornblith S, Adreescu C, Zisook S, Lenze EJ. Antidepressant medication augmented with cognitive-behavioral therapy for generalized anxiety disorder in older adults. Am J Psychiatry. 2013; 170(7): 782-789. Go to original source...
  7. ©vestka J, Doleľal T. Pregabalin - nové nebenzodiazepinové anxiolytikum. Psychiatrie 2007; 11(1): 24-30.
  8. Montgomery S, Emir B, Haswell H, Prieto R. Long-term treatment of anxiety disorders with pregabalin: a 1 year open-label study of safety and tolerability. Curr Med Res Opin. 2013; 29(10): 1223-1230. Go to original source...
  9. Kasper S, Iglesias-Garcia C, Schweizer E, Wilson J, DuBrava S, Prieto R, et al. Pregabalin long-term treatment and assessment of discontinuation in patients with generalized anxiety disorder. Int J Neuropsychopharmacol. 2014; 17(5): 685-695. Go to original source...
  10. SPC Lyrica. www.sukl.cz
  11. Allgulander C. Morbid anxiety as a risk factor in patients with somatic diseases: a review of recent findings. Mind Brain J Psychiatry 2010; 1: 11-19.
  12. Huang KL, Su TP, Chen TJ, Chou YH, Bai YM. Comorbidity of cardiovascular diseases with mood and anxiety disorder: a population based 4-year study. Psychiatry Clin Neurosci 209; 71: 798-804.




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