Psychiatr. praxi. 2023;24(2):70-75 | DOI: 10.36290/psy.2023.015

Serious states induced by taking psychopharmacs and their treatment

prof. MUDr. Eva Češková, CSc.^{1, 2, 3}, PharmDr. Bc. Kateřina Horská, Ph.D.^{4, 5}

¹ Psychiatrická klinika LF MU a FN Brno

² KPN LF Ostravská univerzita

³ Oddělení psychiatrie, FN Ostrava

⁴ Úsek klinické farmacie, Nemocniční lékárna, Fakultní nemocnice Brno

⁵ Ústav farmakologie a toxikologie, Farmaceutická fakulta, Masarykova univerzita, Brno

The article summarizes current knowledge of severe states associated with taking antidepressants and antipsychotics. These states usually require immediate intervention and include acute and tardive dystonia, tardive dyskinesias, neuroleptic malignant syndrome, serotonin syndrome and withdrawal-induced syndrome. Regarding their severity, and sometimes unexpectedly manifestation, they represent severe adverse events subjected to compulsory reporting to State Institute for Drug Control, Department of Pharmacovigilance.

Keywords: acute dystonia, tardive dystonia, tardive dyskinesias, neuroleptic malignant syndrome, serotonin syndrome, withdrawal­induced syndrome, pharmacovigilance.

Accepted: May 31, 2023; Published: June 13, 2023  Show citation