Psychiatr. praxi. 2024;25(2):99-102 | DOI: 10.36290/psy.2024.016

Malignant catatonia in a patient with undifferentiated schizophrenia

MUDr. Martin Vereš, prof. MUDr. Bc. Libor Ustohal, Ph.D.
Psychiatrická klinika, FN Brno

Malignant catatonia is a rare and life-threatening disease. The current ICD or DSM diagnostic systems do not define diagnostic criteria for malignant catatonia, however it is generally defined as a form of catatonia with symptoms of autonomic instability. Without treatment, malignant catatonia carries a high mortality rate, so early diagnosis and treatment is absolutely essential for the patient's prognosis. The preferred therapeutic approach involves the use of benzodiazepines and electroconvulsive therapy, on the other hand, antipsychotic should not be used in treatment of malignant catatonia. Due to the potential for serious somatic complications, consistent monitoring and supportive therapy are also necessary. This case report describes a case of malignant catatonia in a patient previously diagnosed with undifferentiated schizophrenia and a brief summary of current insights into treatment of this condition.

Keywords: malignant catatonia, electroconvulsive therapy, schizophrenia, neuropsychiatric syndrome.

Accepted: May 29, 2024; Published: June 3, 2024  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Vereš M, Ustohal L. Malignant catatonia in a patient with undifferentiated schizophrenia. Psychiatr. praxi. 2024;25(2):99-102. doi: 10.36290/psy.2024.016.
Download citation

References

  1. Kraepelin E. Dementia Praecox and Paraphrenia. Huntington, NY: R.E. Krieger, 1919.
  2. Walther S, Strik W. Catatonia. CNS Spectr. 2016;21(4): 341-348. doi: 10.1017/S1092852916000274. Go to original source... Go to PubMed...
  3. Smolík P. Duševní a behaviorální poruchy. 2. vydání. Praha: Maxdorf, 2002.
  4. International Classification of Diseases, Eleventh Revision (ICD-11), World Health Organization (WHO) 2019/2021 https://icd.who.int/en.
  5. Connell J, Oldham M, Pandharipande P. Malignant Catatonia: A Review for the Intensivist. J Intensive Care Med. 2023 Feb;38(2):137-150. doi:10.1177/08850666221114303. Go to original source... Go to PubMed...
  6. Rasmussen SA, Mazurek MF, Rosebush PI. Catatonia: Our current understanding of its diagnosis, treatment and pathophysiology. World J. Psychiatry. 2016;6(4):391-398. doi: 10.5498/wjp.v6.i4.391. Go to original source... Go to PubMed...
  7. Francis A. Catatonia: Diagnosis, Classification, and Treatment. Curr. Psychiatry Rep.2010; 12(3): 180-18. doi: 10.1007/s11920-010-0113-y. Go to original source... Go to PubMed...
  8. Papežová et al. Naléhavé stavy v psychiatrii, 2. vydání, Maxdorf, Praha 2023.
  9. Desai S, Hirachan T, Toma A, et al. Malignant Catatonia Versus Neuroleptic Malignant Syndrome. Cureus. 2021 Jun 21;13(6):e15818. doi: 10.7759/cureus.15818. Go to original source... Go to PubMed...
  10. Mann SC, Caroff SN, Campbell EC, et al. Malignant Catatonia. Movement Disorder Emergencies: Diagnosis and Treatment. S. J. Frucht a S. Fahn, Ed., in Current Clinical Neurology. Totowa, NJ: Humana Press, 2005:53-67. doi: 10.1385/1-59259-902-8:053. Go to original source...
  11. Pelzer AC, van der Heijden FM, den Boer E. Systematic review of catatonia treatment. Neuropsychiatr. Dis. Treat. 2018;14:317-326. doi: 10.2147/NDT.S147897. Go to original source... Go to PubMed...
  12. Sienaert P, Dhossche DM, Vancampfort D, et al. A Clinical Review of the Treatment of Catatonia. Front. Psychiatry. 2014; 5. Přístup: 4. červen 2023. [Online]. Dostupné z: https://www.frontiersin.org/articles/10.3389/fpsyt.2014.00181 Go to original source... Go to PubMed...
  13. Lloyd JR, Silverman ER, Kugler JL, et al. Electroconvulsive Therapy for Patients with Catatonia: Current Perspectives. Neuropsychiatr. Dis. Treat. 2020;16:2191-2208.doi: 10.2147/NDT.S231573. Go to original source... Go to PubMed...
  14. Cronemeyer M, Schönfeldt-Lecuona C, Gahr M, et al. Malignant catatonia: Severity, treatment and outcome - a systematic case series analysis. World J. Biol. Psychiatry. 2022;23(1):78-86. doi: 10.1080/15622975.2021.1925153. Go to original source... Go to PubMed...




Psychiatry for Practice

Madam, Sir,
please be aware that the website on which you intend to enter, not the general public because it contains technical information about medicines, including advertisements relating to medicinal products. This information and communication professionals are solely under §2 of the Act n.40/1995 Coll. Is active persons authorized to prescribe or supply (hereinafter expert).
Take note that if you are not an expert, you run the risk of danger to their health or the health of other persons, if you the obtained information improperly understood or interpreted, and especially advertising which may be part of this site, or whether you used it for self-diagnosis or medical treatment, whether in relation to each other in person or in relation to others.

I declare:

  1. that I have met the above instruction
  2. I'm an expert within the meaning of the Act n.40/1995 Coll. the regulation of advertising, as amended, and I am aware of the risks that would be a person other than the expert input to these sites exhibited


No

Yes

If your statement is not true, please be aware
that brings the risk of danger to their health or the health of others.