Psychiatrie a umělá inteligence: Nová výzva pro terapeuty?

MUDr. Jan Knopp

Psychiatr. praxi. 2025;26(1):3

Innovations in psychiatric care for women in the perinatal period in the Czech Republic

MUDr. Antonín Šebela, Ph.D.

Psychiatr. praxi. 2025;26(1):5-8 | DOI: 10.36290/psy.2025.001

Perinatal mental health has become a significant focus of interest in recent years, with investment in new specialist perinatal mental health services in some countries. In this review article, we look at the state of perinatal mental health care in European countries and in the Czech Republic. In countries with advanced perinatal care, screening programs for mental disorders in pregnancy and postpartum are implemented, linked to a tiered multidisciplinary system of care and support. Specialized centres and psychiatric wards allowing hospitalization of mothers with children are the culmination of the tiered care. Specialist training is an important...

Treatment of pharmacoresistant states in psychiatry - Part 1: Treatment-resistant schizophrenia

prof. MUDr. Eva Češková, CSc.

Psychiatr. praxi. 2025;26(1):10-14 | DOI: 10.36290/psy.2025.002

The paper is focused on pharmacotherapy of treatment-resistant schizophrenia and exclusion of pseudoresistance. The treatment options including switch, augmentation and combination of antipsychotics are described. Finally, perspective substances are briefly mentioned.

The psychiatry of transgender identity

doc. MUDr. Luděk Fiala, Ph.D., MBA

Psychiatr. praxi. 2025;26(1):16-18 | DOI: 10.36290/psy.2025.003

This review article addresses not only historical but also contemporary approaches to the significant medical problem of transsexuality. It examines the psychiatric processes associated with transsexuality, as well as changes in diagnostic classifications and the evolution of affirmative care practices. The role of psychiatry in the transition process is explored, along with the controversies surrounding the diagnosis of gender dysphoria. It also focuses on the relationship between transgender people and health care. The article aims to present modern perspectives and trends that support the transgender community and advocate for the depathologization...

Pharmacogenetic testing in hospitalized psychiatric patients: benefits and interpretation importance

PharmDr. Ivana Tašková, Ph.D., Mgr. Nicole Šafářová

Psychiatr. praxi. 2025;26(1):19-24 | DOI: 10.36290/psy.2025.004

Our article aims to introduce the reader to pharmacogenetic (PGx) testing in psychiatry, where it currently represents an available and significant tool in personalized medicine. PGx testing enables the adjustment of pharmacotherapy based on patients' genetic predispositions. In psychiatry, PGx testing focuses on polymorphisms in genes responsible for drug metabolism, primarily cytochrome P450 enzymes such as CYP2C19 and CYP2D6. In clinical practice, these tests can help predict drug efficacy or toxicity, thereby improving the safety and effectiveness of pharmacotherapy. PGx testing, which was conducted at the Bohnice Psychiatric Hospital, was done...

Music therapy for children with autism spectrum disorders

PhDr. Markéta Gerlichová, Ph.D., prof. Dr. Dr. Dr. Dr. Wolfgang Mastnak, MUDr. Martin Kučera

Psychiatr. praxi. 2025;26(1):25-29 | DOI: 10.36290/psy.2025.005

The aim of the article is to broaden the awareness of the field of music therapy and the possibilities of applying music therapy approaches, methods and techniques to children with autism spectrum disorder (ASD). It covers the development of scientific knowledge including current findings from research and practice. The article concludes with specific music therapy exercises.

Self-compassion - A cure for anxiety?

Ing. Marek Vich, Ph.D.

Psychiatr. praxi. 2025;26(1):30-35 | DOI: 10.36290/psy.2025.006

Anxiety disorders are currently the most common group of mental disorders, affecting more than 300 million people worldwide. Budgets for the treatment and prevention of these disorders are very limited. The article focuses on self-compassion, which is an available approach to reducing anxiety symptoms as well as potentially treating anxiety disorders. The above text is mainly based on the theory of three systems of emotion regulation, as well as studies focusing on the relationship between self-compassion, anxiety symptoms, emotional attachment and oxytocin. Based on this, recommendations for future studies are presented. For the future development...

Effectiveness of treatment in a psychotherapeutic ward for patients with borderline personality disorder: pilot study

MUDr. Jan Pásztor, prof. MUDr. Ján Praško, CSc., PhDr. Marie Ocisková, Ph.D., Ing. Mgr. Marina Jermářová, Mgr. Karolína Richtrová, MUDr. David Pánek, Ph.D., Mgr. Draga Čermáková, Mgr. et Mgr. Zdeněk Maté, MUDr. Pavel Doubek, Ph.D., MUDr. Martin Hollý

Psychiatr. praxi. 2025;26(1):36-42 | DOI: 10.36290/psy.2025.007

Objective: This study aimed to assess the effectiveness of a six-week therapeutic program combining elements of schema therapy and cognitive-behavioral therapy (CBT) for patients with borderline personality disorder (BPD). Method: The study included 51 patients diagnosed with BPD who participated in the program between January and September 2024. Treatment effectiveness was evaluated using several self-report measures: Borderline Symptom List 23 (BSL-23), Patient Health Questionnaire-9 (PHQ-9), Generalized Anxiety Disorder-7 (GAD-7) and Positive Self-Relation Scale (PSRS). Trained psychologists administered a rating scale Clinical Global Impression...

Case study of a patient with Wernicke's encephalopathy caused by excessive diet

Šimon Pisko, prof. MUDr. Bc. Libor Ustohal, Ph.D.

Psychiatr. praxi. 2025;26(1):43-45 | DOI: 10.36290/psy.2025.008

The patient was admitted to the Department of Psychiatry of Masaryk University and University Hospital Brno with a diagnosis of a delirious state not superimposed on dementia. Based on a more detailed medical history and another assessment, the cause of this state and of the duration of some symptoms was determined as Wernicke's encephalopathy. Treatment was adjusted accordingly using thiamine, which led to further improvement of the patient's condition. Due to persistent ataxia, the patient was subsequently transferred to the neurology rehabilitation department.

Loss of voice as a rare side effect of long-term lithium treatment: A case study of a 32-year-old patient with bipolar affective disorder

MUDr. Eliška Nádvorníková

Psychiatr. praxi. 2025;26(1):46-47 | DOI: 10.36290/psy.2025.009

This case study describes a 32-year-old woman suffering from bipolar affective disorder who was hospitalized in the psychiatric department of CNS Center Třinec due to a voice loss lasting 10 months. The patient had been under psychiatric care since 2013, when she was admitted to the unit shortly after the birth of her daughter, presenting with psychotic symptoms. In 2014, she exhibited signs of a manic episode, necessitating hospitalization and the initiation of lithium as a mood stabilizer. In 2023, following a thorough somatic examination due to the prolonged voice loss, an organic cause for her difficulties was ruled out. Based on the assessment,...

Můžeme léčit schizofrenii tak, aby byl spokojený lékař i pacient?

MUDr. Zuzana Zafarová

Psychiatr. praxi. 2025;26(1):48-54

Farmakoterapie schizofrenie při komorbidním abúzu. Využití kariprazinu v klinické praxi

MUDr. Zuzana Zafarová

Psychiatr. praxi. 2025;26(1):55-62