Psychiatr. pro Praxi, 2005; 5: 229-232

COGNITIVE DISORDERS IN OLD AGE

MUDr. Jiří Konrád
Psychogeriatrický primariát, Psychiatrická léčebna Havlíčkův Brod

The term “cognitive disorders in old age” (inaccurately, in practice often “disorders of memory”) is in the literature described by endless number of syndromes and units. Classification of mainly mild cognitive disorders, which do not fulfil criteria for a dementia and which accompany “normal” aging, is not homogenous and is chaotic. From the historical point of view, we can start with so called “benign senescent forgetfulness” (V. J. Kral 1962), then continue by so called “mild cognitive disorder” and end up with many forms of dementia. In this article, I would like to outline present view on cognitive disorders on the border between normal cognition and dementia – both on those which accompany “normal” cognitive aging and also those termed “mild cognitive disorder”. This condition is a kind of “predementia”. I would like to describe these conditions and classify them based on the information from literature and show an importance of diagnosis of mild cognitive disorders in elderly. These terms do not have rooted Czech equivalents and that why I largely use English terms.

Keywords: Key words: cognitive disorders in old age, mild cognitive disorder, cognitive disorder non-dementia, dementia.

Published: February 1, 2006  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Konrád J. COGNITIVE DISORDERS IN OLD AGE. Psychiatr. praxi. 2005;9(5):229-232.
Download citation

References

  1. Bosma H, van Botel MP, et al. Pesticide exposure and risk of mild cognitive dysfunction. Lancet 2000; 356: 912-913. Go to original source... Go to PubMed...
  2. Ebly E, Hogan D, et al. Cognitive impairment in the nondemented elderly. Results from the Canadian study of health and aging. Arch Neurol.1995; 52: 612-619. Go to original source... Go to PubMed...
  3. Golomb J, Kluger A, Garrard P, Ferris S. Clinician´s Manual on Mild Cognitive Impairment. Science Press. 2001.
  4. Kral VA. Senescent forgefulness: benign and malignant. Can Med Assoc J 1962; 86: 257-260. Go to PubMed...
  5. Larrabee GJ, Crook TH: Estimated prevalence of age-assciated memory impairment derived from standardized test of memory function. Int.Psychogeriatr. 1994; 6: 95-104. Go to original source... Go to PubMed...
  6. Morris J. The Clinical Dementia Rating (CDR): Current version and scorin rules. Neurology 1993; 43: 2412-2414. Go to original source... Go to PubMed...
  7. Palmer K, Wang HX, et al. Differential evolution of cognitive impairment in nondemented older persona: results from the Kungsholmen Project. Am J Psychiatry 2002; 159: 436-442. Go to original source... Go to PubMed...
  8. Petersen R, et al. Donepezil and Vitamin E as Treatment for Mild Cognitive Impairment. Abstrakt, 9th ADRD Conference, Phliadelphia 2004.
  9. Reisberg B, Ferrit SH, et al. The global deterioriation scale for assessment of primary degenerative dementia. Am J Psychiatry 1982; 139: 1136-1139. Go to original source... Go to PubMed...
  10. Roth M, Tym E, et al. A standarized instrument for the diagnosis of mental disorder in the elderly with special reference to early detection of dementia. Br J Psychiatry 1986; 149: 698-709. Go to original source... Go to PubMed...
  11. Saloway S, et al. Efficacy of donepezil in mild cognitive impairment. A randomized placebo-controlled trial. Neurology 2004; 63: 651-657. Go to original source... Go to PubMed...
  12. Seltzer B, et al. Efficacy of Donepezil in Early-Stage Alzheimer Disease A Randomized Placebo-Controlled Trial. Arch Neurol. 2004; 61: 1852-1856. Go to original source... Go to PubMed...
  13. Topinková E. Stárnutí a kognitivní funkce. In: Evžen Růžička, et al: Diferenciální diagnostika a léčba demencí, Galén 2003; 48-49.
  14. Visser PJ, Verhey FRJ, et al. Diagnosis of preclinical Alzheimer´s disease in a clinical setting. Int Psychogeriatr 2002; 13: 411-424. Go to original source... Go to PubMed...
  15. Visser PJ, Verhey FRJ, et al. Predictors of dementia in subjects with mild cognitive impairment - a quantitative meta-analysis. (Abstract). Neurobiol Aging 23: 138.




Psychiatry for Practice

Madam, Sir,
please be aware that the website on which you intend to enter, not the general public because it contains technical information about medicines, including advertisements relating to medicinal products. This information and communication professionals are solely under §2 of the Act n.40/1995 Coll. Is active persons authorized to prescribe or supply (hereinafter expert).
Take note that if you are not an expert, you run the risk of danger to their health or the health of other persons, if you the obtained information improperly understood or interpreted, and especially advertising which may be part of this site, or whether you used it for self-diagnosis or medical treatment, whether in relation to each other in person or in relation to others.

I declare:

  1. that I have met the above instruction
  2. I'm an expert within the meaning of the Act n.40/1995 Coll. the regulation of advertising, as amended, and I am aware of the risks that would be a person other than the expert input to these sites exhibited


No

Yes

If your statement is not true, please be aware
that brings the risk of danger to their health or the health of others.