Pharmacotherapy of anxiety disorders

MUDr. Sylva Racková, MUDr. Luboš Janů Ph.D

Psychiatr. pro Praxi, 2006; 3: 112-116  

Anxiety disorders are very often psychiatric disorders. Without treatment mostly anxiety sypmtoms persist, their course is very often chronical with fluctuation and high risk of the presence of comorbide disorders, suicidal behaviour… In the treatment of anxiety disorders we can use psychotheraphy and pharmacotheraphy. There are antidepressant of the 3rd or the 4th generation the first choice in the psychopharmacotheraphy. Other medication witch is used in the treatment of these disorders are benzodiazepines, betablockers, anticonvulsives.

Antimanic efficacy of second-generation antipsychotics

MUDr. Michal Maršálek CSc

Psychiatr. pro Praxi, 2006; 3: 117-121  

The evidence shows that second-generation antipsychotics are effective in the treatment of bipolar mania, either alone or in combination with traditional mood stabilisers. Use of second-generation antipsychotics is associated with more rapid symptom improvement than in mood stabilisers treatment, and earlier and stronger antimanic effect in combination with lithium or anticonvulsants than in monotherapy. Olanzapine, risperidone, quetiapine, ziprasidone, and aripiprazole demonstrate good therapeutic effect, with no significant differences in antimanic efficacy among these agents. Second-generation antipsychotics, lithium and valproate are recommended...

Antipsychotika v léčbě farmakorezistentní deprese

MUDr. Dagmar Seifertová CSc, MUDr. Martin Bareš Ph.D, MUDr. Milan Kopeček

Psychiatr. pro Praxi, 2006; 3: 122-125  

Clinical trials indicate that approximately 50 % of depressed patients have had an inadequate response to antidepressant therapy. Poor response to adequate antidepressant treatment according treatment guidelines has been termed as treatment resistant depression (TRD). Recent data indicate that atypical antipsychotics can serve as adjunctive as well as alternative agents in the treatment of drug-resistant depressive disorder.

Legal aspects of an acute psychotic patient

MUDr. Svetozár Droba, MUDr. Juraj Lexmann, MUDr. Branislav Moťovský

Psychiatr. pro Praxi, 2006; 3: 126-127  

The article describes legal problems related to an acute psychotic state. A patient with an acute psychotic state is a medical emergency that has to be immediately diagnostically assessed and treated. In a case (in an individual patient) that the condition means a serious threat to the patient or the surrounding or if the lack of treatment could deteriorate patient´s health seriously, a physician is obliged to provide health care measures even without an agreement of the patient. Police can be asked to assist as well. These facts are legally supported in the below mentioned laws that specify duties and competence of health care workers, hospitals and...

New treatment possibilities for bipolar depression

prof. MUDr. Eva Češková CSc

Psychiatr. pro Praxi, 2006; 3: 128-130  

At first general principles of treatment of bipolar disorder are summarized. Further the paper is dealing with the treatment of bipolar depression. In this indication the treatment with atypical antipsychotics is becoming a point of interest. Recently, two double-blind, randomized placebo-controlled studies in patients with bipolar depression comparing olanzapine and combination of olanzapine and fluoxetine with placebo and quetiapine with placebo were published. Quetiapine monotherapy at doses of 300 and 600 mg pro die demonstrated statistically significant improvement in all scales evaluating depressive and anxiety symptomatology, quality of sleep...

Suicidal attempt in children and adolescent - motivation and risk factors

MUDr. Jiří Koutek, doc. MUDr. Jana Kocourková

Psychiatr. pro Praxi, 2006; 3: 131-132  

Authors are addressing problems of suicidal attempts in children and adolescent, mainly from the point of view of declared motivation and detected risk factors. Problems at school, in relationship and family are frequent motives. Risk factors are usually within the family, maladaptation amongst peers, school problems and health status are have been shown to be important. Authors present detected motivation and risk factors in a sample of 38 patients hospitalised for a suicidal attempt.

Depression in Schizophrenia

MUDr. Pavel Mohr, MUDr. Jan Čermák

Psychiatr. pro Praxi, 2006; 3: 133-136  

Concurrent depressive symptoms in schizophrenia are frequent; their incidence is estimated up to 65 %. Depression can occur in any phase of schizophrenia: first episode or chronic illness, during prodromal phase, acute episode, or as a postpsychotic depression. Some authors report a drug-induced depression after treatment with classical antipsychotics. Depression in schizophrenia is associated with increased risk of suicidal behavior. Diagnostics should differentiate comorbid depression from secondary depression, other schizophrenia symptoms, and other psychiatric conditions. Treatment of choice are second-generation antipsychotics (2GA). Their antidepressant...

Edukace při onemocněních psychózou

PhDr. Karolína Malá, Mgr. Hana Navrátilová

Psychiatr. pro Praxi, 2006; 3: 137-139  

Efektivní léčba nespavosti

MUDr. Martin Pretl CSc, MUDr. Jan Vevera

Psychiatr. pro Praxi, 2006; 3: 140-142  

Možnosti psychiatra pri terminálnom pacientovi

MUDr. Alena Mažgútová, doc. MUDr. Igor Ondrejka PhD, MUDr. Robert Olos

Psychiatr. pro Praxi, 2006; 3: 143-145  

Trazodon v léčbě deprese s úzkostí a nespavosti

prof. MUDr. Eva Češková CSc

Psychiatr. pro Praxi, 2006; 3: 146-148  

14. Evropský psychiatrický kongres

doc. MUDr. Ladislav Hosák Ph.D

Psychiatr. pro Praxi, 2006; 3: 149  

Počátky moravské psychiatrie II.

MUDr. Emanuel Doněk, MUDr. Jana Doňková

Psychiatr. pro Praxi, 2006; 3: 150