Psychotropic drugs in pregnancy – do they reduce or increase the risks for the fetus? Part One: antidepressants, antipsychotics

MUDr. Antonín Šebela, MUDr. Jan Hanka, MUDr. Michal Goetz, Ph.D., prof. MUDr. Pavel Mohr, Ph.D.

Psychiatr. praxi 2018; 19(1e)  

There is a trend of increasing prescription rates of psychotropic drugs in females of fertile age, including growing number of pregnant women.The main groups of psychotropics used in psychiatry are antidepressants, antipsychotics, mood stabilizers, and anxiolytics. Both drugs anduntreated psychiatric disorders represent risk factors for adverse pregnancy outcomes and poor neonatal adaptation of an exposed newborn.We review current published data on the effects of prenatal exposure to untreated depressive and psychotic disorders, antidepressants andantipsychotics on the fetus development, pregnancy outcomes, and neonatal adaptation. Available data suggest...

Psychotropic drugs in pregnancy – do they reduce or increase the risks for the fetus? Part two: mood stabilizers, anxiolytics

MUDr. Antonín Šebela, MUDr. Eliška Nosková, MUDr. Michal Goetz, Ph.D., prof. MUDr. Pavel Mohr, Ph.D.

Psychiatr. praxi 2018; 19(1e)  

There is an increasing number of women, who plan to become or already are pregnant, and concurrently use psychotropic drugs for mental illness.Most of psychotropic drugs pass through the placenta to developing fetus and thus may affect the embryogenesis. On the other hand, untreatedpsychiatric disorder represents a risk factor of adverse pregnancy outcome and poor neonatal adaptation of an exposed newborn, as well. We reviewcurrent published data on the impact of prenatal exposure to untreated bipolar disorder and anxiety disorders, and effects of mood stabilizers andanxiolytics on the fetus development, pregnancy outcome, and neonatal adaptation....

Drug induced movement disorders – basics for pharmacologists

doc. MUDr. Marek Baláž, Ph.D., prof. MUDr. Tomáš Kašpárek, Ph.D.

Psychiatr. praxi 2018; 19(1e)  

Drug induced movement disorders may appear after number of pharmacological treatments. Dopaminergic-treatment related chorea in Parkinson’sdisease and tardive dyskinesia are the ones most well described.Determination of the type of hyperkinesia is very important for the diagnosis of drug-induced movement disorders, as the treatments differ across the various clinical phenomena. Treatments are based on tapering of dose or discontinuation of offending drug but may include alsotargeted pharmacotherapy, botulinum toxin or deep brain stimulation.

Safety environment as an important atribute in reducing the risk of suicide in inpatients

MUDr. Adam Žaludek, MBA

Psychiatr. praxi 2018; 19(1e): e3-e11 | DOI: 10.36290/psy.2018.027  

One of the most important root causes of finished inpatient suicide is the lack of safety environment. The aim of the article to highlight theimportance of the topic and to point out some possible ways how to built a safe environment in acute psychiatric wards in the Czech Republic.

E-verze 1/18

Psychiatr. praxi 2018; 19(1e)