Kde se v nás bere krutost?

prof. PhDr. Pavel Říčan, CSc.

Psychiatr. praxi. 2011;12(1):3  

Contemporary acute treatment trends of manic episode of bipolar disorder

doc.MUDr.Radovan Přikryl, Ph.D.

Psychiatr. praxi. 2011;12(1):9-12  

Bipolar disorder is a common serious psychiatric illness involving recurrent episodes of depression and mood elevation. Although the last decade has seen important advances in the pharmacotherapy of bipolar disorder, there remain substantial unmet needs in the management of this illness. Lithium, valproate and the second generation antipsychotics (aripiprazole, quetiapine, olanzapine, risperidone or ziprasidone) represent current emphasis of acute pharmacological treatment of manic episode. The acute treatment of manic episode of bipolar disorder should be choosen according to contemporary guidelines with regard to subjective tolerability and...

Alzheimer disease and the engagement of informal carers in a fight for the quality of life

MUDr.Kateřina Sheardová

Psychiatr. praxi. 2011;12(1):13-18  

A successful therapy of dementia should positively influence cognitive functions as well as the quality of life and behavioral and psychological symptoms. This goal can be achieved by combination of pharmacological and non-pharmacological approaches. Diseases manifesting with dementia are a heavy burden not only for the patients but also for caregivers caring for their relatives at home. The article reviews current therapeutic approaches to dementia with the focus on non-pharmacological interventions that informal carers might try or access in the home background.

Specific features of victimization of rape victims

MUDr.Petra Sejbalová, MUDr.Helena Reguli

Psychiatr. praxi. 2011;12(1):19-21  

The paper deals with the difference of the psychic trauma experienced by a victim of rape or other sexual assault. The definition is provided and the manifestations of primary victimization are listed. The causes resulting in and affecting secondary victimization are dealt with in detail. A case report demonstrates the individual factors affecting the development, progression and severity of post-traumatic stress disorder in a girl rape victim and the resulting consequences. The options of reducing the manifestations of secondary victimization within the medical practice as well as law enforcement authorities are discussed. behaviour.

Efficacy and safety of escitalopram in elderly persons: pooled analysis of five open-label observational studies

prof.MUDr.Jiří Horáček, Ph.D.

Psychiatr. praxi. 2011;12(1):22-26  

Using the data from five open-label observational studies of the efficacy and safety of escitalopram (Cipralex®) organized by the original manufacturer (Lundbeck) in the Czech Republic between 2003 and 2007 (N = 27183), an analysis of the efficacy and occurrence of adverse effects in persons of younger and older age was performed. The main inclusion criterion was the indication of treatment with escitalopram. The most common reason for commencing treatment with escitalopram was depression (37.1 %) followed by the category of anxiety and neurotic disorders (28.7 %). The assessment of age effect was based on two different age levels. The...

Occurence of atypical antipsychotics on sexual dysfunction in male schizophrenic patients

MUC Jana Ščerbová, MUC Sandra Bogorová, prof.MUDr.Alexandra Žourková, CSc., Monika Večeřová

Psychiatr. praxi. 2011;12(1):27-29  

The paper presents the frequency of sexual dysfunction according to ASEX scale in 78 schizophrenic males treated with atypical antipsychotics (olanzapine, risperidone, amisulprid, clozapine, quetiapin). Dysfunctional scores of ASEX scale were found in 23 patients treated with antipsychotics (18 %). Difference among antipsychotics has been hardly eveluated for small number of patients in subgroups. The most occurrence of dysfunction was found in quetiapine subgroup, 4 from 6 patients had dysfunctional ASEX score.

Do we know how to dose Risperdal Consta?

prof.MUDr.Eva Češková, CSc., MUDr.Jiří Kopřiva

Psychiatr. praxi. 2011;12(1):30-32  

Non-adherence was the main reason for development of depot (= long-acting injections, LAI) antipsychotics. Risperdal Consta is the first available LAI of 2nd generation antipsychotics. Czech Republic has participated at the study e-STAR (electronic Schizophrenia Treatment Adherence Registry), an international, prospective, observational study assessing use of Risperdal Consta in a normal clinical practice setting. This analysis deals with dosage of Consta and compares dosing patterns from e-STAR in Czech Republic with other European countries. Methods: Treatment related data were collected at baseline and at 3 month intervals for 24 months....

Rehabilitation methods focused at occupational skills of persons with cognitive deficit due to schizophrenia

PhDr.Mgr.Lada Furmaníková, Ph.D.

Psychiatr. praxi. 2011;12(1):33-37  

The paper is dedicated to the rehabilitation methods that should encourage the development of social and occupational skills of persons with cognitive deficits due to schizophrenia. The reason for this focus is, first, the demonstrated influence of cognitive deficit for the skills associated with social functioning and independent living, second, the relative resistance of the cognitive deficit to the pharmacologistic intervention and also to the rehabilitation procedures aimed at improving of the cognitive functions (the cognitive rehabilitation). The text presents selected recommendatiosns for the realization of the social skills training...

New approved indication of ziprasidone in the treatment of bipolar disorder in children and adolescents

prof.MUDr.Ivana Drtílková, CSc.

Psychiatr. praxi. 2011;12(1):38-41  

Recent, placebo-controlled studies have shown that atypical antipsychotics can significantly reduce manic symptoms in children and adolescents with bipolar disorder. Children appear to be at higher risk than adults for a number of adverse effects, such as extrapyramidal symptoms or metabolic and endocrine changes. Ziprasidone treatment was associated with clinically and statistically significant improvement in children and adolescents with bipolar disorders. Ziprasidone was well tolerated with no statistically significant increase in body weight and without changes of metabolic and endocrine values.

Autodidaktický test 1/2011

Psychiatr. praxi. 2011;12(1):42